| Science Driver | Campus |
| Artificial Intelligence for Robotics | San Diego State University |
| Biomedical Informatics | San Diego State University |
| Artificial Intelligence for Business Applications | San Diego State University |
| Biochemistry and Quantum Materials | CSU San Bernardino |
| Digital Archeology | CSU San Bernardino |
| Chemistry for Thin Films | CSU San Bernardino |
| Earthquake Monitoring | Cal Poly-Humboldt |
| Hydrological Modeling | Cal Poly-Humboldt |
| Conservation Genomics | Cal Poly-Humboldt |
| Computational Chemistry | CSU Stanislaus |
| Particle Physics | CSU Stanislaus |
| X-Ray Tomography | CSU Stanislaus |
| Hyperdimensional Computing | CSU San Marcos |
| Financial Modeling | CSU Northridge |
| Laser Plasma Physics | CSU Channel Islands |
TIDE
Technology Infrastructure for Data Exploration